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Dr. Mark Leo Graham II, MD

Accepting New Patients

(590 Ratings)

Specializes in: Medical Oncology, Adult Oncology and Adult Hematology

Mayo Medical School

210 Ashville Avenue Suite 440
Cary, NC 27518

(919) 350-8585

Dr. Mark Leo Graham II, MD is a medical oncologist in Cary, NC specializing in medical oncology, adult oncology and adult hematology. He graduated from Mayo Medical School. Dr. Mark Leo Graham II, MD is affiliated with WakeMed Health & Hospitals.

Office Locations

WakeMed Health & Hospitals

210 Ashville Avenue Suite 440
Cary, NC 27518

(919) 235-1391

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In The News (see more mentions in the news)

“The Doerfler family would like to thank Tom's medical team at WakeMed Cary Hospital, especially Dr. Michael Malik, Dr. Sharad Vora, Dr. Mark Graham, and Jessica Johnson.”—"Thomas Taylor Doerfler", Raleigh News & Observer, August 2015

“A special thanks from the family goes to Dr. Mark Graham and staff of Waverly Oncology and Dr. Camille Frazier-Mills of Duke Cardiology for their compassionate care of both Mom and...”—"James Edward Taggart", Raleigh News & Observer, January 2015

“"I think she understood that keeping going was inspirational to other people who were in the same boat she was in," Dr. Mark Graham, Yow's longtime oncologist, said Saturday.”—"Longtime NC State women's coach Kay Yow dies at 66", Desert News, January 2009

Noteworthy Medicare Patient Procedures Performed by Dr. Mark Leo Graham II, MD in 2023

Click on any procedure below to see further details on volume and pricing among Medicare patients.

Top 5%

By Volume:

inpatient hospital care

In 2023, Dr. Mark Leo Graham II, MD performed more inpatient hospital care (for patient admitted to hospital) procedures for Medicare patients than 95% of providers in related specialties within North Carolina.

Medicare Procedure and Patient Information

2013 Medicare Procedure Volume

The top procedures that Dr. Mark Leo Graham II, MD treated as a medical oncologist in Cary, NC during 2013 were lab tests, blood draw, hospital care and minimally invasive procedures.

Volume of procedures performed by Dr. Mark Leo Graham II, MD for Medicare patients.

biological response modifier (BRM) therapy	522
blood draw	2652
chemotherapy	522
doctor visit	1618
hormone therapy	109
hospital care	730
inpatient care	681
lab tests	3169
minimally invasive procedures	702
outpatient care	49
port flush	33

2013 Medicare Patient Data

Information about Medicare patients treated by Dr. Mark Leo Graham II, MD.

**Gender**
Male	225
Female	657

**Ethnicity**
Non-Hispanic White	743
Black	98
Hispanic	15
Asian	12
Other	14
Native American	0

**Age**
From 65 to 74	442
From 75 to 84	267
85 and over	108
Less than 65	65

Conditions of Medicare patients treated by Dr. Mark Leo Graham II, MD in 2013

The most common conditions of Medicare patients that Dr. Mark Leo Graham II, MD treated during 2013 were hypertension, high cholesterol, cancer and chronic kidney disease.

Hypertension	67
High Cholesterol	54
Stroke	4
Ischemic Heart Disease	29
Depression	17
Chronic Kidney Disease	29
Asthma	8
Osteoperosis	12
Atrial Fibrilation	13
Heart Failure	19
Chronic Obstructive Pulmonary Disease	14
Diabetes	28
Dementia	9
Cancer	53

Medicare Procedure and Patient Information

2014 Medicare Procedure Volume

The top procedures that Dr. Mark Leo Graham II, MD treated as a medical oncologist in Cary, NC during 2014 were lab tests, blood draw, hospital care and inpatient care.

Volume of procedures performed by Dr. Mark Leo Graham II, MD for Medicare patients.

biological response modifier (BRM) therapy	432
blood draw	2374
chemotherapy	432
doctor visit	1466
hospital care	616
inpatient care	571
lab tests	2947
minimally invasive procedures	557
outpatient care	45
port flush	43

2014 Medicare Patient Data

Information about Medicare patients treated by Dr. Mark Leo Graham II, MD.

**Gender**
Male	222
Female	646

**Ethnicity**
Non-Hispanic White	748
Black	79
Hispanic	14
Asian	13
Other	14
Native American	0

**Age**
From 65 to 74	418
From 75 to 84	258
85 and over	120
Less than 65	72

Conditions of Medicare patients treated by Dr. Mark Leo Graham II, MD in 2014

The most common conditions of Medicare patients that Dr. Mark Leo Graham II, MD treated during 2014 were hypertension, high cholesterol, cancer and chronic kidney disease.

Hypertension	65
High Cholesterol	53
Stroke	4
Ischemic Heart Disease	29
Depression	20
Chronic Kidney Disease	32
Asthma	7
Osteoperosis	14
Atrial Fibrilation	12
Heart Failure	19
Chronic Obstructive Pulmonary Disease	13
Diabetes	26
Dementia	9
Cancer	51

Medicare Procedure and Patient Information

2015 Medicare Procedure Volume

The top procedures that Dr. Mark Leo Graham II, MD treated as a medical oncologist in Cary, NC during 2015 were lab tests, blood draw, minimally invasive procedures and hospital care.

Volume of procedures performed by Dr. Mark Leo Graham II, MD for Medicare patients.

biological response modifier (BRM) therapy	389
blood draw	1575
chemotherapy	389
doctor visit	1545
hormone therapy	97
hospital care	536
inpatient care	475
lab tests	2074
minimally invasive procedures	563
outpatient care	16

2015 Medicare Patient Data

Information about Medicare patients treated by Dr. Mark Leo Graham II, MD.

**Gender**
Male	274
Female	1128

**Ethnicity**
Non-Hispanic White	1208
Black	122
Hispanic	24
Asian	26
Other	22
Native American	0

**Age**
From 65 to 74	772
From 75 to 84	402
85 and over	146
Less than 65	82

Conditions of Medicare patients treated by Dr. Mark Leo Graham II, MD in 2015

The most common conditions of Medicare patients that Dr. Mark Leo Graham II, MD treated during 2015 were cancer, hypertension, high cholesterol and chronic kidney disease.

Hypertension	61
High Cholesterol	53
Stroke	5
Ischemic Heart Disease	25
Depression	20
Chronic Kidney Disease	25
Asthma	10
Osteoperosis	13
Atrial Fibrilation	11
Heart Failure	16
Chronic Obstructive Pulmonary Disease	15
Diabetes	23
Dementia	9
Cancer	70

Medicare Procedure and Patient Information

2016 Medicare Procedure Volume

The top procedures that Dr. Mark Leo Graham II, MD treated as a medical oncologist in Cary, NC during 2016 were lab tests, blood draw, hospital care and inpatient care.

Volume of procedures performed by Dr. Mark Leo Graham II, MD for Medicare patients.

biological response modifier (BRM) therapy	411
blood draw	1569
chemotherapy	411
doctor visit	1649
hormone therapy	176
hospital care	718
inpatient care	616
lab tests	2084
minimally invasive procedures	566
outpatient care	23

2016 Medicare Patient Data

Information about Medicare patients treated by Dr. Mark Leo Graham II, MD.

**Gender**
Male	167
Female	607

**Ethnicity**
Non-Hispanic White	667
Black	71
Hispanic	15
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	417
From 75 to 84	228
85 and over	91
Less than 65	38

Conditions of Medicare patients treated by Dr. Mark Leo Graham II, MD in 2016

The most common conditions of Medicare patients that Dr. Mark Leo Graham II, MD treated during 2016 were cancer, hypertension, high cholesterol and chronic kidney disease.

Hypertension	65
High Cholesterol	50
Stroke	5
Ischemic Heart Disease	28
Depression	18
Chronic Kidney Disease	31
Asthma	18
Osteoperosis	12
Atrial Fibrilation	13
Heart Failure	16
Chronic Obstructive Pulmonary Disease	16
Diabetes	24
Dementia	12
Cancer	70

Medicare Procedure and Patient Information

2017 Medicare Procedure Volume

The top procedures that Dr. Mark Leo Graham II, MD treated as a medical oncologist in Cary, NC during 2017 were lab tests, blood draw, minimally invasive procedures and hospital care.

Volume of procedures performed by Dr. Mark Leo Graham II, MD for Medicare patients.

biological response modifier (BRM) therapy	863
blood draw	2275
chemotherapy	863
doctor visit	2457
hormone therapy	244
hospital care	1076
inpatient care	875
lab tests	3746
minimally invasive procedures	1178
outpatient care	61

2017 Medicare Patient Data

Information about Medicare patients treated by Dr. Mark Leo Graham II, MD.

**Gender**
Male	290
Female	853

**Ethnicity**
Non-Hispanic White	982
Black	110
Hispanic	15
Asian	17
Other	19
Native American	0

**Age**
From 65 to 74	567
From 75 to 84	361
85 and over	145
Less than 65	70

Conditions of Medicare patients treated by Dr. Mark Leo Graham II, MD in 2017

The most common conditions of Medicare patients that Dr. Mark Leo Graham II, MD treated during 2017 were hypertension, cancer, high cholesterol and chronic kidney disease.

Hypertension	65
High Cholesterol	45
Stroke	6
Ischemic Heart Disease	27
Depression	21
Chronic Kidney Disease	34
Asthma	6
Osteoperosis	13
Atrial Fibrilation	13
Heart Failure	17
Chronic Obstructive Pulmonary Disease	15
Diabetes	25
Dementia	12
Cancer	56

Medicare Procedure and Patient Information

2018 Medicare Procedure Volume

The top procedures that Dr. Mark Leo Graham II, MD treated as a medical oncologist in Cary, NC during 2018 were lab tests, blood draw, minimally invasive procedures and hospital care.

Volume of procedures performed by Dr. Mark Leo Graham II, MD for Medicare patients.

biological response modifier (BRM) therapy	646
blood draw	1956
chemotherapy	646
doctor visit	1955
hormone therapy	211
hospital care	794
inpatient care	719
lab tests	2588
minimally invasive procedures	869

2018 Medicare Patient Data

Information about Medicare patients treated by Dr. Mark Leo Graham II, MD.

**Gender**
Male	222
Female	777

**Ethnicity**
Non-Hispanic White	848
Black	97
Hispanic	20
Asian	17
Other	17
Native American	0

**Age**
From 65 to 74	495
From 75 to 84	331
85 and over	115
Less than 65	58

Conditions of Medicare patients treated by Dr. Mark Leo Graham II, MD in 2018

The most common conditions of Medicare patients that Dr. Mark Leo Graham II, MD treated during 2018 were cancer, hypertension, high cholesterol and chronic kidney disease.

Hypertension	62
High Cholesterol	54
Stroke	5
Ischemic Heart Disease	27
Depression	23
Chronic Kidney Disease	33
Asthma	6
Osteoperosis	13
Atrial Fibrilation	11
Heart Failure	17
Chronic Obstructive Pulmonary Disease	14
Diabetes	26
Dementia	11
Cancer	63

Medicare Procedure and Patient Information

2019 Medicare Procedure Volume

The top procedures that Dr. Mark Leo Graham II, MD treated as a medical oncologist in Cary, NC during 2019 were lab tests, blood draw, minimally invasive procedures and hospital care.

Volume of procedures performed by Dr. Mark Leo Graham II, MD for Medicare patients.

biological response modifier (BRM) therapy	645
blood draw	2327
bone marrow tests	15
chemotherapy	645
diagnostic procedures	15
doctor visit	2253
hormone therapy	176
hospital care	675
inpatient care	675
lab tests	2980
minimally invasive procedures	862

2019 Medicare Patient Data

Information about Medicare patients treated by Dr. Mark Leo Graham II, MD.

**Gender**
Male	269
Female	842

**Ethnicity**
Non-Hispanic White	953
Black	94
Hispanic	0
Asian	20
Other	26
Native American	0

**Age**
From 65 to 74	563
From 75 to 84	367
85 and over	122
Less than 65	59

Conditions of Medicare patients treated by Dr. Mark Leo Graham II, MD in 2019

The most common conditions of Medicare patients that Dr. Mark Leo Graham II, MD treated during 2019 were cancer, hypertension, high cholesterol and chronic kidney disease.

Hypertension	62
High Cholesterol	58
Stroke	4
Ischemic Heart Disease	28
Depression	24
Chronic Kidney Disease	32
Asthma	6
Osteoperosis	14
Atrial Fibrilation	11
Heart Failure	16
Chronic Obstructive Pulmonary Disease	13
Diabetes	27
Dementia	11
Cancer	62

Medicare Procedure and Patient Information

2020 Medicare Procedure Volume

The top procedures that Dr. Mark Leo Graham II, MD treated as a medical oncologist in Cary, NC during 2020 were lab tests, blood draw, minimally invasive procedures and hospital care.

Volume of procedures performed by Dr. Mark Leo Graham II, MD for Medicare patients.

biological response modifier (BRM) therapy	668
blood draw	2540
chemotherapy	668
doctor visit	2496
hormone therapy	243
hospital care	880
inpatient care	880
lab tests	3455
minimally invasive procedures	899
port flush	40

2020 Medicare Patient Data

Information about Medicare patients treated by Dr. Mark Leo Graham II, MD.

**Gender**
Male	304
Female	883

**Ethnicity**
Non-Hispanic White	1014
Black	105
Hispanic	0
Asian	24
Other	25
Native American	0

**Age**
From 65 to 74	583
From 75 to 84	400
85 and over	139
Less than 65	65

Conditions of Medicare patients treated by Dr. Mark Leo Graham II, MD in 2020

The most common conditions of Medicare patients that Dr. Mark Leo Graham II, MD treated during 2020 were hypertension, cancer, high cholesterol and chronic kidney disease.

Hypertension	62
High Cholesterol	57
Stroke	4
Ischemic Heart Disease	27
Depression	23
Chronic Kidney Disease	33
Asthma	7
Osteoperosis	14
Atrial Fibrilation	11
Heart Failure	16
Chronic Obstructive Pulmonary Disease	12
Diabetes	27
Dementia	10
Cancer	60

Medicare Procedure and Patient Information

2021 Medicare Procedure Volume

The top procedures that Dr. Mark Leo Graham II, MD treated as a medical oncologist in Cary, NC during 2021 were lab tests, blood draw, hospital care and inpatient care.

Volume of procedures performed by Dr. Mark Leo Graham II, MD for Medicare patients.

biological response modifier (BRM) therapy	596
blood draw	3303
chemotherapy	596
doctor visit	2865
hormone therapy	275
hospital care	1135
inpatient care	1113
lab tests	4370
minimally invasive procedures	848
outpatient care	22
port flush	45

2021 Medicare Patient Data

Information about Medicare patients treated by Dr. Mark Leo Graham II, MD.

**Gender**
Male	339
Female	973

**Ethnicity**
Non-Hispanic White	1111
Black	112
Hispanic	0
Asian	31
Other	28
Native American	0

**Age**
From 65 to 74	597
From 75 to 84	463
85 and over	180
Less than 65	72

Conditions of Medicare patients treated by Dr. Mark Leo Graham II, MD in 2021

The most common conditions of Medicare patients that Dr. Mark Leo Graham II, MD treated during 2021 were hypertension, high cholesterol, cancer and chronic kidney disease.

Hypertension	65
High Cholesterol	60
Stroke	5
Ischemic Heart Disease	30
Depression	22
Chronic Kidney Disease	37
Asthma	6
Osteoperosis	15
Atrial Fibrilation	12
Heart Failure	17
Chronic Obstructive Pulmonary Disease	12
Diabetes	26
Dementia	11
Cancer	56

Medicare Procedure and Patient Information

2022 Medicare Procedure Volume

The top procedures that Dr. Mark Leo Graham II, MD treated as a medical oncologist in Cary, NC during 2022 were lab tests, blood draw, hospital care and inpatient care.

Volume of procedures performed by Dr. Mark Leo Graham II, MD for Medicare patients.

biological response modifier (BRM) therapy	534
blood draw	2440
chemotherapy	534
doctor visit	2251
hormone therapy	140
hospital care	1224
inpatient care	1211
lab tests	3272
minimally invasive procedures	764
outpatient care	13

2022 Medicare Patient Data

Information about Medicare patients treated by Dr. Mark Leo Graham II, MD.

**Gender**
Male	329
Female	837

**Ethnicity**
Non-Hispanic White	981
Black	94
Hispanic	29
Asian	30
Other	0
Native American	0

**Age**
From 65 to 74	510
From 75 to 84	437
85 and over	175
Less than 65	44

Conditions of Medicare patients treated by Dr. Mark Leo Graham II, MD in 2022

The most common conditions of Medicare patients that Dr. Mark Leo Graham II, MD treated during 2022 were high cholesterol, hypertension, cancer and chronic kidney disease.

Hypertension	72
High Cholesterol	75
Stroke	8
Ischemic Heart Disease	25
Depression	22
Chronic Kidney Disease	26
Asthma	9
Osteoperosis	23
Atrial Fibrilation	19
Heart Failure	18
Chronic Obstructive Pulmonary Disease	17
Diabetes	26
Dementia	9
Cancer	61

Medicare Procedure and Patient Information

Average Medicare Procedure Volume From 2013 - 2022

Volume of procedures performed by Dr. Mark Leo Graham II, MD for Medicare patients.

The highest averages for the top procedures that Dr. Mark Leo Graham II, MD treated as a medical oncologist in Cary, NC were lab tests, blood draw, hospital care and inpatient care.

biological response modifier (BRM) therapy	570
blood draw	2301
bone marrow tests	15
chemotherapy	570
diagnostic procedures	15
doctor visit	2055
hormone therapy	185
hospital care	838
inpatient care	781
lab tests	3068
minimally invasive procedures	780
outpatient care	32

Average Medicare Patient Data From 2013 - 2022

Information about Medicare patients treated by Dr. Mark Leo Graham II, MD.

**Gender**
Female	820
Male	264

**Ethnicity**
Black / African American	98
Asian / Pacific Islander	19
Non-Hispanic White	925
Hispanic	13
Native American / Alaskan Native	0
Other	16

**Age**
85 and over	134
75 to 84	351
Less than 65	62
65 to 74	536

Average of Total of Conditions of Medicare patients treated by Dr. Mark Leo Graham II, MD From 2013 - 2022

The highest averages of the most common conditions of Medicare patients that Dr. Mark Leo Graham II, MD treated were hypertension, cancer, high cholesterol and chronic kidney disease.

Hypertension	64
High Cholesterol	55
Stroke	5
Ischemic Heart Disease	27
Depression	21
Chronic Kidney Disease	31
Asthma	8
Osteoporosis	14
Heart Failure	17
Chronic Obstructive Pulmonary Disease	14
Diabetes	25
Atrial Fibrillation	12
Cancer	60
Dementia	10

Education & Training

Dr. Mark Leo Graham II, MD graduated from Mayo Medical School. He completed residency at Duke University Medical Center. He has a state license in North Carolina.

Medical School: Mayo Medical School

Residency: Duke University Medical Center

Licensed In: North Carolina

Affiliations & Hospitals

Dr. Mark Leo Graham II, MD is associated with these hospitals and organizations:

WakeMed Health & Hospitals

Ratings & Reviews

Dr. Mark Leo Graham II, MD has an exceptional overall rating with an average of 4.9 out of 5 stars based on 590 ratings. We collect ratings and reviews of Dr. Mark Leo Graham II, MD from all over the web to help you find the right in Cary, NC.

4.9

Overall Rating

(590 Ratings)

Leave a Review

General Payments

These charts describe general payments received by Dr. Mark Leo Graham II, MD. Doctors may receive payments for a number of reasons, including meal compensation, travel compensation, and consulting.

**Payments by Company**
Janssen Biotech, Inc.	$649 IMBRUVICA $212	Erleada $142	ZYTIGA $124	DARZALEX $114	PROCRIT $44	Other $12
Novartis Pharmaceuticals Corporation	$514 AFINITOR $168	TASIGNA $76	KISQALI $74	NON BRAND $43	PROMACTA $36	Other $116
Eli Lilly and Company	$499 $499
E.R. Squibb & Sons, L.L.C.	$455 OPDIVO $258	SPRYCEL $89	ELIQUIS $80	EMPLICITI $15	YERVOY $12
Pfizer Inc.	$454 IBRANCE $102	XTANDI $82	TALZENNA $56	ELIQUIS $43	LORBRENA $25	Other $145
Other	$4,296 Abraxane $180	Nerlynx $144	SOLIRIS $142	IMBRUVICA $129	LYNPARZA $124	Other $3,578

**Types of Payments**
Food and Beverage	$5,729
Education	$539
Gift	$392
Travel and Lodging	$206

Research Payments

Dr. Mark Leo Graham II, MD has received 125 research payments totaling $465,170.

Ownership and Interest Payments

This table describes ownership payments received by Dr. Mark Leo Graham II, MD.

DARA Biosciences, Inc.

2014

$0.00

Physician Covered Recipient

None

Biography

Dr. Mark Graham specializes in adult hematology, adult oncology, and medical oncology and practices in Cary, NC. Dr. Graham is professionally affiliated with WakeMed Health & Hospitals. After completing medical school at Mayo Medical School, he performed his residency at Duke University Medical Center. The average patient rating for Dr. Graham is 5.0 stars (out of 5). According to WakeMed Health & Hospitals, he is currently accepting new patients at his office in Cary, NC.