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Home > MO Providers > Allergists & Immunologists

Dr. Zachary Edward Rubin, MD

(Zachary Rubin)

(No ratings)

Specializes in: Allergy & Immunology

Case Western Reserve University School of Medicine (2015)

Professional interests include: asthma, eczema, allergies

24600 W. 127th Street Building B Suite 110
Plainfield, IL 60585

(815) 609-8286

Dr. Zachary Edward Rubin, MD is an allergist and immunologist in Saint Louis, MO specializing in allergy & immunology. He graduated from Case Western Reserve University School of Medicine in 2015 and has 10 years of experience. Dr. Zachary Edward Rubin, MD is affiliated with Endeavor Health and OAK BROOK ALLERGISTS SC.

Office Locations

1 Barnes Jew Hosp Plaza
Saint Louis, MO 63110

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Endeavor Health

1220 Hobson Road Suite 114
Naperville, IL 60540

(630) 961-2960

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1740 W Taylor Street
Chicago, IL 60612

1-866-600-2273

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Endeavor Health

24600 W. 127th Street Building B Suite 110
Plainfield, IL 60585

(815) 609-8286

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Endeavor Health

360 W Butterfield Road Suite 140
Elmhurst, IL 60126

(630) 574-0460

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Endeavor Health

6800 S. Main Street Suite 110
Downers Grove, IL 60516

(630) 789-0575

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Some issues Dr. Zachary Edward Rubin, MD can help you with:

Asthma

Asthma is a chronic lung disease where the tissue and airways of the lungs become extremely sensitive to certain substances. When these substances are breathed in, the lungs become inflamed. The muscles around the airways tighten and squeeze the lungs, and passages within the lungs swell and tighten. The airways themselves produce mucus, which further clogs the tightened, swollen airways. A person having an asthma attack finds it very difficult to breathe, and a severe attack can even be fatal.

Asthma affects people of all ages, but people with asthma are most often diagnosed as children. Symptoms can include wheezing, a tight feeling in the chest, shortness of breath, and coughing. Some people have mild symptoms all the time, and some people have no symptoms at all, but everyone with asthma is susceptible to occasional severe attacks or flare-ups of symptoms when they are exposed to triggers. Triggers vary widely but can include:

Allergens (dust mites, pet fur, mold, pollen, grass)
Irritants (smoke, pollution, dust, chemicals)
Viral infections
Physical activity, especially outdoors
Certain medications or chemicals in foods (aspirin, sulfites)

Treatment for most asthma patients involves three steps. Patients learn what their asthma triggers are and avoid them. They take a daily control medication, usually an inhaled corticosteroid, to reduce inflammation in the lungs. Also, they have rescue medication with them at all times to take in case of a severe attack. These quick-acting inhaled medications relax the muscles around the airways and allow the lungs to open up for air.

There is no cure for asthma, but with treatment it should not interfere with daily life and activities.

In The News (see more mentions in the news)

“But about two-thirds of children with allergies are diagnosed by age 3, said Dr. Zachary Rubin, a pediatric allergist in Illinois.”—"Peanut Allergies Have Plummeted in Children, Study Shows", New York Times, October 2025

“Dr. Zachary Rubin, a double board-certified pediatrician who specializes in immunology and allergy treatment, said in a Substack post that Ladapo s words are "a calculated move in the ongoing...”—"Florida s move to end vaccine mandates may deepen skepticism in Black communities, health experts warn", CNN, September 2025

“Popular medical content creator Dr. Zachary E. Rubin, a pediatrician certified in allergy and immunology, shared a TikTok video in which he explained the Florida outbreak is a "result of the lies...”—"Raw Milk Sold For 'Non-Human Consumption' Linked To Florida Outbreak", Huff Post, August 2025

Noteworthy Medicare Patient Procedures Performed by Dr. Zachary Edward Rubin, MD in 2023

Click on any procedure below to see further details on volume and pricing among Medicare patients.

Top 5%

By Affordability:

allergen immunotherapy

allergy skin testing

allergy testing

immunotherapy

percutaneous allergy test

skin testing

subcutaneous allergen immunotherapy

In 2023, Dr. Zachary Edward Rubin, MD had a list price for allergen immunotherapy, allergy skin testing, allergy testing, immunotherapy, percutaneous allergy test, skin testing, and subcutaneous allergen immunotherapy (allergy shots) that was lower than the list prices billed to Medicare by 95% of providers in related specialties within Missouri. Actual amounts paid by patients can vary widely depending on a number of factors, including insurance coverage. A lower list price, however, might mean lower fees when paying without insurance.

Top 10%

By Volume:

subcutaneous allergen immunotherapy

In 2023, Dr. Zachary Edward Rubin, MD performed more subcutaneous allergen immunotherapy (allergy shots) procedures for Medicare patients than 90% of providers in related specialties within Missouri.

Medicare Procedure and Patient Information

2021 Medicare Procedure Volume

The top procedures that Dr. Zachary Edward Rubin, MD treated as an allergist and immunologist in Saint Louis, MO during 2021 were immunotherapy, injections, skin testing and allergy testing.

Volume of procedures performed by Dr. Zachary Edward Rubin, MD for Medicare patients.

allergy testing	76
doctor visit	25
immunotherapy	606
injections	606
skin testing	76

2021 Medicare Patient Data

Information about Medicare patients treated by Dr. Zachary Edward Rubin, MD.

**Gender**
Male	61
Female	74

**Ethnicity**
Non-Hispanic White	116
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	81
From 75 to 84	41
85 and over	0
Less than 65	0

Conditions of Medicare patients treated by Dr. Zachary Edward Rubin, MD in 2021

The most common conditions of Medicare patients that Dr. Zachary Edward Rubin, MD treated during 2021 were high cholesterol, hypertension, diabetes and ischemic heart disease.

Hypertension	56
High Cholesterol	64
Stroke	0
Ischemic Heart Disease	20
Depression	15
Chronic Kidney Disease	19
Asthma	16
Osteoperosis	12
Atrial Fibrilation	0
Heart Failure	0
Chronic Obstructive Pulmonary Disease	8
Diabetes	23
Dementia	0
Cancer	9

Medicare Procedure and Patient Information

2022 Medicare Procedure Volume

The top procedures that Dr. Zachary Edward Rubin, MD treated as an allergist and immunologist in Saint Louis, MO during 2022 were immunotherapy, injections, skin testing and minimally invasive procedures.

Volume of procedures performed by Dr. Zachary Edward Rubin, MD for Medicare patients.

allergy testing	325
doctor visit	61
immunotherapy	963
injections	963
minimally invasive procedures	325
skin testing	325

2022 Medicare Patient Data

Information about Medicare patients treated by Dr. Zachary Edward Rubin, MD.

**Gender**
Male	69
Female	107

**Ethnicity**
Non-Hispanic White	154
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	101
From 75 to 84	59
85 and over	0
Less than 65	0

Conditions of Medicare patients treated by Dr. Zachary Edward Rubin, MD in 2022

The most common conditions of Medicare patients that Dr. Zachary Edward Rubin, MD treated during 2022 were high cholesterol, hypertension, asthma and diabetes.

Hypertension	60
High Cholesterol	75
Stroke	0
Ischemic Heart Disease	15
Depression	14
Chronic Kidney Disease	14
Asthma	30
Osteoperosis	16
Atrial Fibrilation	7
Heart Failure	0
Chronic Obstructive Pulmonary Disease	11
Diabetes	21
Dementia	0
Cancer	15

Medicare Procedure and Patient Information

2023 Medicare Procedure Volume

The top procedures that Dr. Zachary Edward Rubin, MD treated as an allergist and immunologist in Saint Louis, MO during 2023 were immunotherapy, injections, skin testing and minimally invasive procedures.

Volume of procedures performed by Dr. Zachary Edward Rubin, MD for Medicare patients.

allergy testing	531
doctor visit	56
immunotherapy	1066
injections	1066
minimally invasive procedures	531
skin testing	531

2023 Medicare Patient Data

Information about Medicare patients treated by Dr. Zachary Edward Rubin, MD.

**Gender**
Male	63
Female	109

**Ethnicity**
Non-Hispanic White	156
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	94
From 75 to 84	63
85 and over	0
Less than 65	0

Conditions of Medicare patients treated by Dr. Zachary Edward Rubin, MD in 2023

The most common conditions of Medicare patients that Dr. Zachary Edward Rubin, MD treated during 2023 were high cholesterol, hypertension, asthma and diabetes.

Hypertension	55
High Cholesterol	75
Stroke	0
Ischemic Heart Disease	19
Depression	18
Chronic Kidney Disease	12
Asthma	30
Osteoperosis	17
Atrial Fibrilation	8
Heart Failure	0
Chronic Obstructive Pulmonary Disease	16
Diabetes	19
Dementia	0
Cancer	14

Medicare Procedure and Patient Information

Average Medicare Procedure Volume From 2021 - 2023

Volume of procedures performed by Dr. Zachary Edward Rubin, MD for Medicare patients.

The highest averages for the top procedures that Dr. Zachary Edward Rubin, MD treated as an allergist and immunologist in Saint Louis, MO were immunotherapy, injections, minimally invasive procedures and skin testing.

allergy testing	310
doctor visit	47
immunotherapy	878
injections	878
minimally invasive procedures	428
skin testing	310

Average Medicare Patient Data From 2021 - 2023

Information about Medicare patients treated by Dr. Zachary Edward Rubin, MD.

**Gender**
Male	64
Female	96

**Ethnicity**
Black / African American	0
Asian / Pacific Islander	0
Non-Hispanic White	142
Hispanic	0
Native American / Alaskan Native	0
Other	0

**Age**
75 to 84	54
85 and over	0
Less than 65	0
65 to 74	92

Average of Total of Conditions of Medicare patients treated by Dr. Zachary Edward Rubin, MD From 2021 - 2023

The highest averages of the most common conditions of Medicare patients that Dr. Zachary Edward Rubin, MD treated were high cholesterol, hypertension, asthma and diabetes.

Hypertension	57
High Cholesterol	71
Stroke	0
Ischemic Heart Disease	18
Depression	15
Chronic Kidney Disease	15
Asthma	25
Osteoporosis	15
Heart Failure	0
Chronic Obstructive Pulmonary Disease	11
Diabetes	21
Atrial Fibrillation	5
Dementia	0
Cancer	12

Education & Training

Dr. Zachary Edward Rubin, MD graduated from Case Western Reserve University School of Medicine in 2015. He is certified by the American Board of Allergy and Immunology and has a state license in Illinois.

Medical School: Case Western Reserve University School of Medicine (2015)

Board Certification: American Board of Allergy and Immunology (2020)

Licensed In: Illinois

Affiliations & Hospitals

Dr. Zachary Edward Rubin, MD is associated with these hospitals and organizations:

Endeavor Health

OAK BROOK ALLERGISTS SC

Ratings & Reviews

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General Payments

These charts describe general payments received by Dr. Zachary Edward Rubin, MD. Doctors may receive payments for a number of reasons, including meal compensation, travel compensation, and consulting.

**Payments by Company**
AstraZeneca Pharmaceuticals LP	$53,398 AIRSUPRA $27,990	TEZSPIRE $10,279	FASENRA $120	BREZTRI $14	$14,995
GlaxoSmithKline, LLC.	$786 NUCALA $585	TRELEGY ELLIPTA $201
GENZYME CORPORATION	$768 NO PRODUCT DISCUSSED $400	DUPIXENT $354	$14
Regeneron Healthcare Solutions, Inc.	$696 DUPIXENT $696
SANOFI-AVENTIS U.S. LLC	$250 DUPIXENT $250
Other	$1,218 XOLAIR $220	Xhance $193	Hizentra $99	Auvi-Q $95	AirDuo Digihaler $94	Other $516

**Types of Payments**
Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program	$36,350
Consulting Fee	$14,000
Food and Beverage	$5,063
Travel and Lodging	$1,021
Grant	$400
Other	$282

Biography

Dr. Zachary Rubin's specialty is pediatric allergy & immunology. He trained at a hospital affiliated with the University of Illinois at Chicago for residency. His areas of expertise include asthma, sinus problems, and allergy testing. Dr. Rubin's professional affiliations include Edward Hospital and Elmhurst Hospital.